Synairgen (SNG ) shares jump 32.96% to 34.82p as data provides ‘strong clinical rationale’
Today, Synarigen has unveiled the first full set of data analysis from its Phase 3 SPRINTER trial evaluating the efficacy and safety of its lead asset in patients hospitalised with COVID-19.
The respiratory company is currently developing its lead asset SNG001, an investigational formulation for inhalation containing the broad-spectrum antiviral protein interferon beta.
SPRINTER was a randomised, placebo-controlled, double-blind clinical trial assessing the efficacy and safety of SNG001 for treating adults hospitalised due to COVID-19 who required treatment with supplemental oxygen. Initially, the study did not meet its primary endpoints.
However, closer analysis of the data has revealed its underlying potential in high-risk groups, with researchers finding that the risk of progression to severe disease and death compared to a medicinally inert placebo in the patients trialled was reduced by 70% by taking SNG001.
Vast Resources (VAST ) shares jump 32.53% to 1.1p as it repays outstanding bonds
Shares in Vast Resources have jumped as high as 81% on Monday after it repaid in full the outstanding bonds owed to Atlas Special Opportunities following a subscription and placing.
The mining firm has secured a $4m asset backed debt facility from A&T Investments SARL (Alpha) arranged by Alpha Credit SA, a Swiss investment banking and asset management boutique, and raised in aggregate £3.243m through a placing of 463m shares at 0.7p each.
In practice, the company’s repayment means that Atlas no longer has any conversion or any right to call for the issue of Vast’s ordinary shares and removes any share dilution concerns.
Vast sees the refinancing as such “a pivotal development”, particularly when coupled with the various operational developments which it said is “gaining pace” at Baita Plai and elsewhere.
Clontarf Energy (CLON ) shares rise 25.30% to 0.52p ahead of May drilling operations
In an update to shareholders on Thursday, the company said its Valaris MS-1 rig is anchored in the
Dampier outer harbour and that it is scheduled to commence tow to the Sasanof-1 well.
The move was expected to occur today. Prior to this, Western Gas’ drilling operations team were deployed to the field and on board the MS-1 rig undertaking pre-mobilisation checks.
Drilling operations at the Sasanof-1 exploration well are expected to start on 24 May 2022.
(RWS ) shares fall 18.30% to 361.7p as private equity group backs out of bid
Baring Private Equity Asia Fund VIII, the Hong Kong-based group which in recent weeks has indicated interest in buying RWS, says it no longer intends to make an offer for the business.
In response, the software company stated that BPEA’s interest was unsolicited and that it did not lead to any proposal. The firm also expressed ongoing confidence in its growth strategy.
The Board of RWS informed investors that it believes the company has a strong future based on its “clearly defined strategy.” The Company added that it is focused on the actions and investments which support this stated strategy and its five year accelerated growth plan.