Avacta Group Plc
AVCT:LN
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Overview
Company Profile
Avacta Therapeutics is a clinical-stage life sciences company expanding the reach of highly potent cancer therapies with the pre|CISION® platform. pre|CISION® is a proprietary warhead delivery system based on a tumor-specific protease (fibroblast activation protein or FAP) that is designed to concentrate highly potent warheads in the tumor microenvironment while sparing normal tissues. Our innovative pipeline consists of pre|CISION® peptide drug conjugates (PDC) or Affimer® drug conjugates (AffDC) that leverage the tumor-specific release mechanism, providing unique benefits over traditional antibody drug conjugates
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Corporate
Board of Directors
Christina Coughlin
CEO
Christina Coughlin, MD, PhD is the former Chief Executive Officer of CytoImmune Therapeutics. Dr. Coughlin joined CytoImmune from Rubius Therapeutics, Inc. where she served as the Chief Medical Officer and led the clinical development, translational medicine and regulatory efforts in the allogeneic red cell therapy platform. Prior to Rubius, Dr. Coughlin was with Tmunity Therapeutics, Inc., where she served as Chief Medical Officer and was responsible for the development of autologous CAR-T and TCR-T cellular therapies. Dr. Coughlin served as the Chief Medical Officer for Immunocore, Ltd where she led the development of KimmtrakTM, recently approved for the treatment of metastatic uveal melanoma. Dr. Coughlin has held other leadership roles in the pharmaceutical and biotechnology fields in her career including Oncology Asset Team Leader at Pfizer and Clinical Program Team Lead at Novartis. Dr. Coughlin is an oncologist and immunologist, having received her M.D. and Ph.D. from the University of Pennsylvania and completed fellowships in Hematology and Oncology at the Children’s Hospital of Philadelphia and in the Translational Research Group under the direction of Carl June, M.D. at the University of Pennsylvania.
Group Senior Management
Michael Vinegrad
Group Communications Director
After obtaining a BA (hons) in history from Nottingham Trent University, Michael undertook a career in marketing and communications, initially with the NHS and Department of Health. He moved into the life sciences industry working for Bioventus and Smith & Nephew. Here he helped to significantly grow their digital presence and delivered a number of successful international medical device marketing campaigns, as well as working on internal and external communications. Michael joined Avacta Group in 2014, where he now leads the communications function.